Dr. Bayati made at least seven technical errors. These are listed in topical groups. --> indicates a comment appraising the error. ------------------------- A: -->Misplaced overemphasis of the significance of low phosphorous, with failure to point out that the measured value of 0.1 mg/dL (versus 2.5-4.9 normal) was only after about a day and a half of hemodialysis and hemoperfusion, and that such hypophosphatemia is fairly common in treatment of methanol poisoning unless the hemodialysis is phosphorus-enriched. (https://www.ncbi.nlm.nih.gov/pubmed/15818551) ------------------------- GROUP B: Three errors in Dr. Bayati's view of the symptoms and toxicity of methanol: B1) "Heparin, sodium bicarbonate, and metabolic problems caused the bleeding and other lesions observed in Chuck's brain." "Bleeding causes edema, necrosis, and inflammation in the brain." "Bleeding observed in Chuck’s brain on the CT scan of June 14th and during autopsy was caused by the high doses of hepa- rin given to Chuck in the hospital." --> No. Methanol works the other way around. Inflammation is caused by immune system response to cells with identifier proteins switched to "foreign" by formaldehyde. The brain is then pushed down onto sharp ridges on the bottom interior of the skull, whence the bleeding. Heparin might exacerbate the problem, but not cause it specifically on the bottom of the brain. B2) "Formic acid has been shown to inhibit cytochrome oxidase in the mictochondria [16-18]. --> No. Formaldehyde has a much stronger degradation of cytochrome c oxidase. B3) "Formic acid measurements in the blood and other biological samples should be performed in all suspected methanol- poisoning cases to confirm that metabolic acidosis is caused by the accumulation of formic acid." --> No. The acidosis of methanol poisoning is due to lactic acid from formaldehyde-induced anaerobic metabolism. This is an earlier and much stronger effect than from formic acid. And instead of one molecule of formaldehyde being oxidized to one molecule of formic acid, the hampering of a cytochrome c oxidase molecule by a molecule of formaldehyde causes continual production of many lactic acid molecules by anaerobic metabolism. ------------------------- GROP C: Three errors showing Dr. Bayati not being able to see that both methanol and hyper-creatine could be involved. C1) "The four Gatorade bottles tested and used as evidence and reported to contain methanol are not the same bottles of Gatorade containing the creatine that Diane and Chuck added to Gatorade on June 11, 2000. --> Absurd. C2) "Measurements of methanol in the blood taken in Chuck's case represent a false positive:" --> Absurd. C3) "Increased creatine bioavability caused acute renal failure." --> Not likely. In-situ formaldehyde from circulating methanol was probably the dominant cause of renal failure.